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Giovanni Palleschi

NEFROCENTER, Medica San Carlo, Frascati (Rome, Italy)

Giovanni Palleschi, MD, Ph.D., obtained an MD in Medicine and Surgery in 1997 and a specialization in Urology in 2002. He also obtained two master’s degrees in Laparoscopy in 2005 and 2022, respectively, and a Ph.D. in Anatomy, Plastic Surgery and Dermatology in 2008. He previously taught courses in medicine and nursing. He is the author of seventy manuscripts and scientific books. He has been a speaker and organizer of numerous scientific events and a co-investigator in clinical trials. Dr. Palleschi is a previous board member of the Italian Society of Urodynamics (SIUD), the scientific committees of SIUD, the Italian Society of Urology (SIU), and the European Society of Urology (EAU), and several teaching committees. He is the winner of six scientific awards. He is a reviewer and editor for journals, including Frontiers in Urology, Biology, Toxins, Diagnostics, and Biomedicine. He is a member of the Italian Botulinum Toxin Network and a consultant for the Dialysis and Kidney Transplant Registry.

1books edited

3chapters authored

Latest work with IntechOpen by Giovanni Palleschi

Among inflammatory disorders of the urinary tract, cystitis is the most common. A significant increase in the prevalence of this condition is reported by epidemiological investigations, and its diagnostic and therapeutic approach often represents a challenge. Bacterial cystitis is becoming difficult to treat, especially if chronic or recurrent, due to the increase of drug resistance among the responsible pathogens. Chronic non-infectious cystitis is also difficult to treat because its pathophysiologic mechanisms are still not completely understood. This book provides a comprehensive overview of bladder inflammation, focusing on etiopathogenesis, pathophysiology, and diagnostic and therapeutic approaches to the main types of infectious and non-infectious cystitis in both adults and children. It also addresses radiation cystitis as well as iatrogenic cystitis.

Cystitis

Cystitis

Edited by Giovanni Palleschi

Chapters authored

Quality of Life in Neurogenic Bladder Patients and Improvement after Botulinum Toxin Injection

By Giovanni Palleschi and Antonio Cardi

Various neurogenic conditions may determine an altered function of the bladder and urethral sphincters leading to urinary symptoms. Among these symptoms, loss of urine is considered the most bothersome, and recent literature has proposed that urinary incontinence and poor quality of life should be considered as associated conditions. Urinary incontinence is responsible for reducing the enjoyment of life, including loss of self-confidence and limitation of social activity; it is also associated with anxiety, depression, and deterioration in sexual life, and reduced physical activity. Conservative treatments represent a first-line therapeutic approach to neurogenic urinary disorders, followed by oral medications. However, these treatments often do not provide complete recovery from symptoms, especially from urinary incontinence. Onabotulimun toxin A has proven to be safe and effective for treating neurogenic urinary incontinence and its use is associated with a strong improvement of patients’ quality of life. Furthermore, this treatment lowers the risk of severe complications to the upper urinary tract, reducing the need for hospitalization. Quality of life improvement as well as clinical efficacy must be considered targets of the therapy, and the use of onabotulimun toxin A for treating neurogenic urinary incontinence reaches both these goals.

Part of the book: Botulinum Toxin

Introductory Chapter: Presenting an Overview on the Main Clinical, Diagnostic and Therapeutic Aspects of Human Cystitis

By Giovanni Palleschi

Part of the book: Cystitis

Related collaborators

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Tanta University , Egypt

Anna V. Reznik

Mohamed H. Zahran

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San Giovanni Addolorato Hospital, Rome

Ibrahim Alowidah

King Saud Medical City , Saudi Arabia

Diaa-Eldin Taha

Kafrelsheikh University , Egypt

Mohammad Osama Makkeiah

Damascus University , Syria

Tamara Kosyreva

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Peoples' Friendship University of Russia , Russia