Anil Tombak

Mersin University Turkey

Prof. Dr. Anil Tombak, MD, was born on April 25, 1976. He graduated from Gazi Anatolian High School in 1994, and then from Çukurova University Medical Faculty in 2000. Subsequently, he was trained at Mersin University Medical Faculty Internal Medicine Department, and after internal medicine specialization became a fellow of hematology at the same university. He became a hematologist in 2013 while still working at Mersin University Medical Faculty, Department of Internal Medicine—Hematology, Mersin, Turkey. He has performed research in several fields, and has more than 50 publications in (inter)national journals and numerous papers in scientific conferences. He has received several awards and is a member of the Turkish Society of Hematology. Dr. Tombak is married and has two children.

2books edited

3chapters authored

Latest work with IntechOpen by Anil Tombak

Red blood cells constitute approximately 40% of the total amount of blood and 99% of shaped elements of blood. Their major function is oxygen transportation and this makes erythrocytes "the basis of life." However, as readers will see in this book, erythrocytes have a lot of different, important functions in our body. With this book, it is planned to collect current information related to "erythrocytes." The book has been divided into two sections. The first section includes information about the roles of erythrocytes in the physiological and pathophysiological processes. The second section includes information on the future perspectives of erythrocytes like their therapeutic applications in medicine. This book will be a stepping stone for scientists who are rapidly advancing their science journey.

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Erythrocyte

Edited by Anil Tombak

Books edited

Blood Groups

Edited by Anil Tombak

Chapters authored

Red Blood Cells and Relation to Thrombosis

By Anil Tombak

Blood coagulation and thrombin generation are primarily a function of platelets, coagulation factors, and endothelial cells. Red blood cells (RBCs) have generally been viewed as innocent bystanders in the clotting process. However, there has been a steadily growing clinical data revealing the active roles of erythrocytes in hemostasis. RBCs may contribute to thrombosis in several ways. In polycythemia, RBCs increase blood viscosity and marginate platelets toward the endothelium. The increased incidence of thrombosis is also associated with hemolytic anemia, especially with sickle cell disease and paroxysmal nocturnal hemoglobinuria. RBCs express phosphatidylserine and microparticles, supporting thrombin generation. They interact with platelets, endothelial cells, and fibrinogen, and these interactions lead their incorporation into the thrombi. The presence of RBCs in clots suppresses plasmin generation and reduces clot dissolution. Decreasing thrombus RBC content would accelerate thrombus resolution. In conclusion, RBCs are important complements of the complex reactions of clot formation.

Part of the book: Transfusion Medicine and Scientific Developments

Introductory Chapter: Blood Groups - From Past to the Future

By Anil Tombak

Part of the book: Blood Groups

Introductory Chapter: Erythrocytes - Basis of Life

By Anil Tombak

Part of the book: Erythrocyte

Anil Tombak

Latest work with IntechOpen by Anil Tombak

Erythrocyte

Books edited

Blood Groups

Chapters authored

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