Meet the editor

Fabrice Mutelet is an associate professor in Chemical Engineering Thermodynamics at Ecole Nationale Superieure des Industries Chimiques – University of Lorraine (ENSIC-LRGP), France. He received his doctorate in 2001 from the University of Lorraine. He is a reviewer for more than twenty leading international journals and has published more than 120 research papers. His research interests include suitable sustainable solvents for

chemical processes, the reduction of CO2 emissions, and the measurement and correlation of phase diagrams for complex systems.

Contents

*by Fabrice Mutelet*

Multiphysics Modelling Approach

of Thermally Unstable Analytes

of Organic Compounds in Ionic Liquids

*by Amel Ayad, Fabrice Mutelet and Amina Negadi*

*by Igor G. Zenkevich*

*and Khaldoun Bachari*

**Preface III**

**Chapter 1 1**

**Chapter 2 5**

**Chapter 3 25**

**Chapter 4 47**

**Chapter 5 65**

**Chapter 6 89**

Recent Advances in Targeting Clinical Volatile Organic Compounds (VOC)

Introductory Chapter: Recent Advances in Gas Chromatography

Reactive Transport and Its Implications on Heavy Oil HTGC Analysis – A Coupled Thermo-Hydro-Chemical (THC)

*Bahman Tohidi, Roda Bounaceur and François Montel*

*by Diana Margarita Hernandez-Baez, Alastair Reid, Antonin Chapoy,* 

Features and New Examples of Gas Chromatographic Separation

*by Imadeddine Azzouz, Mohammad Sharif Khan, Andrew C. Bishop* 

Exploring the Mysteries of *Cannabis* through Gas Chromatography *by María Teresa García-Valverde, Verónica Sánchez de Medina, Verónica Codesido, Jesús Hidalgo-García and Carlos Ferreiro-Vera*

Temperature-Dependent Linear Solvation Energy Relationship for the Determination of Gas-Liquid Partition Coefficients

## Contents


Preface

In the 1940s, Martin and Synge invented partition chromatography, laying the foundation for gas chromatography. Nowadays, the theory of chromatography and its basic principles are well described in the literature. Gas chromatography is probably one of the main techniques used in laboratories worldwide. Over the last several decades, researchers have pushed the limits of this technique by developing new procedures for the separation of components of systems found in biomedical or petrochemical industries. Inverse gas chromatography, a variation of conventional gas chromatography, was developed for the characterization of polymers, glass and carbon fibers, coal, and solid foods. In this technique, the material under investigation is placed in the chromatographic column and numerous probes are injected to provide information on the polarity or the surface of the sample.

This book includes contributions from experts in different domains. It beings with a chapter devoted to the identification and the validation of volatile organic compounds (VOCs) resulting from various diseases. It summarizes important technological advancements used to pre-concentrate and analyze VOCs. The next chapter describes recent advances in the analysis of Cannabis sativa L. by gas chromatography. The chapter includes two studies in which the thermal decomposition of analytes occurs during gas chromatography separation. Another chapter gives insight into the analysis of the reactive transport process occurring during the analysis of heavy oil hydrocarbons inside a high-temperature gas chromatography column. It also deals with those interrelated physicochemical processes generated by the application of a thermo-hydro-chemical (THC)-coupled multiphysics approach. The final chapter presents a thermodynamic model based on physico-chemical parameters measured using inverse gas chromatography.

This book is designed for those who have some acquaintance with gas chromatography, although we believe that it will be useful for beginners as well. Four chapters are devoted to specific techniques used in the medical and petrochemical industries.

> **Fabrice Mutelet** University of Lorraine,

> > Nancy, France
