**Acknowledgements**

The authors acknowledge Fundação para a Ciência e Tecnologia (FCT) for the PhD grants – PD/BDE/142837/2018, SFRH/BD/130218/2017, and PD/BDE/114353/ 2016. The authors also acknowledge the projects UID/EMS/00481/2019-FCT and CENTRO-01-0145-FEDER-022083 - Centro Portugal Regional Operational Programme (Centro2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF).
