**3.4 Duration of treatment**

276 Psoriasis

advantages and disadvantages. Many patients appreciate the simplicity of infliximab's dosage schedule: half a day in hospital every eight weeks seems much easier than more regular injections at home. Patients often say: "at least, with the drip, I can forget about psoriasis and its treatment completely for two whole months". Patients do not have to go to the pharmacy on a regular basis, keep boxes in the family refrigerator, or have a nurse

On the other hand, some patients fear the hospital environment and prefer treatments they can manage independently. This explains the figure of 31 patients who began infliximab as second- or third-line treatment. Of these patients, the majority had begun with etanercept, with a clinical response deemed insufficient. Some had begun with adalimumab, with a subsequent secondary clinical relapse. Some patients used these two products before beginning infliximab. One patient had received ustekinumab, with a good clinical result, but

repeatedly visit their house (figure 1).

Fig. 1. Infusion in specialized unit

the development of a paradoxical eczematous reaction.

The average duration of treatment (stopped on the day of database analysis) is 604 days, with extremes of 14 and 1666 days. This duration is long enough to draw conclusions, at least partial ones. The 14-day duration corresponds to a treatment stopped due to side effects.
