**6.1 Relapse of comorbidities**

WR following BS is associated with and significantly predicted relapse of T2DM [12, 70]. At 10 year follow up, T2DM relapse was dependent on the extent of WR [70]. Patients with no WR had no relapse of their diabetes [70]. While, patients with mild regain (increase body weight > 5 kg from nadir) and severe regain (> 10 kg from nadir) had 5% and 17% relapse rates respectively [70]. Among 1406 RYGB patients with WR during the first year after reaching nadir weight, 25.8% and *Weight Regain and Insufficient Weight Loss after Bariatric Surgery: A Call for Action DOI: http://dx.doi.org/10.5772/intechopen.94848*

46.2% of participants experienced progression of hyperlipidemia and hypertension respectively [9].
