**10. Conclusions**

There is no cure for MM until today, however the recent advancements in management approaches provide hope for complete remission with improved survival. ASCT is currently considered the standard of care for fit newly diagnosed MM patients. Multiple combinations of PIs and IMIDs, salvaged with MAs, CTs, and other chemotherapeutic agents have been evaluated and available for both ASCTeligibles as well as ineligible settings, while further studies are still running.
