Meet the editors

Dr. Mila Kovacheva-Slavova graduated from Medical University, Sofia, Bulgaria, where she obtained her Ph.D. in the area of pancreatic disorders. She is an assistant professor in the Department of Gastroenterology, Medical University, Sofia, and is an active member in many national and international research projects. Dr. Kovacheva-Slavova's research interests include diagnosis, therapy, and follow-up of pancreatic diseases, gastrointestinal

autoimmune diseases, tumors of the digestive system, and *Helicobacter pylori* infection. Her scientific work has been presented at numerous meetings and awarded at prestigious congresses in Europe, the United States, and South America.

Prof. Vladimirov is head of the Department of Gastroenterology, Medical University, Sofia, Bulgaria, where he obtained his Ph.D. in the area of endoscopy treatment of bile ducts and pancreatic diseases. His main research interests are gastrointestinal diagnostic and therapeutic endoscopy, peptic diseases, Helicobacter pylori infection, and tumors of the digestive system. His main activities include digestive endoscopy, education (pre- and

post-graduate), and clinical research. Dr. Vladimirov is a coordinator of many national and international projects. He has published more than 200 articles in Bulgarian and international medical journals. Dr. Vladimirov is a member of several Bulgarian and European scientific societies.

Contents

Introductory Chapter: Pancreatic Cancer *by Mila Dimitrova Kovacheva-Slavova and Borislav Georgiev Vladimirov*

*Aihua Gong, Dongqing Wang and Haitao Zhu*

for the Treatment of Pancreatic Cancer

of Pancreatic Cancer

*and Beat Gloor*

Pancreatic Cancer

*and Luis Ubillos*

Advance in Pancreatic Cancer Diagnosis and Therapy *by Xiaojie Cai, Jie Gao, Yanfang Liu, Ming Wang, Qiulian Ma,* 

KRas4BG12C/D/PDE6δ Heterodimeric Molecular Complex: A Target Molecular Multicomplex for the Identification and Evaluation of Nontoxic Pharmacological Compounds

*by Paola Briseño-Díaz, Dora Emma Velez-Uriza, Pedro Cruz-Nova, Martiniano Bello Ramirez, Jose Correa-Basurto, Rosaura Hernandez-Rivas,* 

Computer Assistance in the Minimally Invasive Ablation Treatment

*by Benjamin Eigl, Andreas Andreou, Matthias Peterhans, Stefan Weber* 

Current Systemic Treatment Options for Metastatic and Unresectable

*by Christian Caglevic, Mauricio Mahave, Cristobal Sanhueza* 

An Overview of Pancreatic Neuroendocrine Tumors

*by Neha Sharma and Deepti Sharma*

*Ma del Rocio Thompson Bonilla and Miguel Ángel Vargas Mejía*

**Preface XI**

**Chapter 1 1**

**Chapter 2 5**

**Chapter 3 25**

**Chapter 4 41**

**Chapter 5 61**

**Chapter 6 79**
