**8. Conclusions**

Public health prevention on CRC screening uptake is very important for reducing the incidence and mortality. Population will benefit more with an early CRC screening uptake. There are multiple barriers that can hinder person from undergoing CRC screening for early prevention, detection and treatment. Majority of these barriers encountered regarding the poor rates of CRC screening are similar across countries in Asia, except for specific barriers that are due to unique circumstances. Lack of knowledge/education is the most critical barrier that is linked to a majority of other barriers. Continuous effort is important to reduce CRC related morbidity and mortality. Previous evidence showed positive effect on promoting CRC screening among community. The increased uptake of CRC screening also needs multicomponent in the intervention such as health communication, employer as well as the commitment from the physician itself. The enhancement of multicomponent screening programme will leads to successful rate of CRC screening uptake among the community.

**References**

September 2020].

3632.

[1] Arnold, M., Sierra, M. S., Laversanne, M., Soerjomataram, I., Jemal, A. & Bray, F. Global Patterns and Trends in Colorectal Cancer Incidence and Mortality. Gut 2017;66(4): 683-691.

*Public Health: Prevention*

[2] World Health Oganization. 2018. Cancer https://www.who.int/newsroom/fact-sheets/detail/cancer [1

*DOI: http://dx.doi.org/10.5772/intechopen.94396*

Immunochemical and Guaiac-Based Fecal Occult Blood Test in Screening and Surveillance for Advanced

Colorectal Neoplasms: A Meta-Analysis.

[8] Hewitson, P., Glasziou, P. P., Irwig, L., Towler, B. & Watson, E. 2007. Screening for Colorectal Cancer Using

[9] Zorzi, M., Fedeli, U., Schievano, E., Bovo, E., Guzzinati, S., Baracco, S., Fedato, C., Saugo, M. & Dei Tos, A. P. Impact on Colorectal Cancer Mortality of Screening Programmes Based on the Faecal Immunochemical Test. Gut 2015;

[10] Uppara, M., Adaba, F., Askari, A., Clark, S., Hanna, G., Athanasiou, T. & Faiz, O. A Systematic Review and Meta-Analysis of the Diagnostic Accuracy of Pyruvate Kinase M2 Isoenzymatic Assay in Diagnosing Colorectal Cancer. World journal of surgical oncology 2015;

[11] Miller, E. A., Pinsky, P. F., Schoen, R. E., Prorok, P. C. & Church, T. R. Effect of Flexible Sigmoidoscopy Screening on Colorectal Cancer Incidence and Mortality: Long-Term Follow-up of the Randomised Us Plco Cancer Screening Trial. The Lancet Gastroenterology & Hepatology 2019;4

[12] Atkin, W., Wooldrage, K., Parkin, D. M., Kralj-Hans, I., Macrae, E., Shah, U., Duffy, S. & Cross, A. J. Long Term

Sigmoidoscopy Screening after 17 Years

Sigmoidoscopy Screening Randomised Controlled Trial. The Lancet 2017; 389

[13] Brenner, H., Chang–Claude, J., Jansen, L., Knebel, P., Stock, C. &

Effects of Once-Only Flexible

of Follow-Up: The Uk Flexible

(10076): 1299-1311.

the Faecal Occult Blood Test, Hemoccult. Cochrane Database of

Systematic Reviews (1).

64(5): 784-790.

13(1): 48.

(2): 101-110.

[3] Navarro, M., Nicolas, A., Ferrandez, A. & Lanas, A. Colorectal Cancer Population Screening Programs

Worldwide in 2016: An Update. World journal of gastroenterology 2017;23(20):

[4] Wolf, A. M., Fontham, E. T., Church, T. R., Flowers, C. R., Guerra, C. E., Lamonte, S. J., Etzioni, R., Mckenna, M. T., Oeffinger, K. C. & Shih, Y. C. T. Colorectal Cancer Screening for Average-Risk Adults: 2018 Guideline Update from the American Cancer Society. CA: a cancer journal for clinicians 2018; 68(4): 250-281.

[5] Lin, J. S., Piper, M. A., Perdue, L. A., Rutter, C. M., Webber, E. M., O'connor,

Preventive Services Task Force. Jama

[6] Kamil, N. a. M., Said, H. R. H. M., Azmi, A. N., Sidek, A. S. M., Siew, C. N.

Kamaruzaman, H. F., Nor, I. M., Yusof, M. a. M., Rahim, N. A., Adnan, N. N. N., Baharom, S., Abdullah, S., Merican, S. a.

E., Smith, N. & Whitlock, E. P. Screening for Colorectal Cancer: Updated Evidence Report and Systematic Review for the Us

2016; 315(23): 2576-2594.

G., Jaya, F., Ahmad, H. Z.,

Malaysia 80.

**29**

A., Poh, T. H., Yazid, T. N. T. & Zainudin, Z. 2017. Management of Colorectal Carcinoma Clinical Practice Guidelines. Putrajaya Ministry of Health

[7] Zhu, M., Xu, X., Nie, F., Tong, J., Xiao, S. & Ran, Z. 2010. Comparison of
