**Author details**

Bhaswatee Das1 , Bipasha Choudhury1 , Aditya Kumar1 \* and Vishwa Jyoti Baruah<sup>2</sup> \*

1 Department of Molecular Biology and Biotechnology, Tezpur University, Tezpur, Assam, India

2 Centre for Biotechnology and Bioinformatics, Dibrugarh University, Dibrugarh, Assam, India

\*Address all correspondence to: aditya@tezu.ernet.in; vishwabaruah@gmail.com

© 2021 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

**203**

*Genomic Instability and DNA Repair in Cancer DOI: http://dx.doi.org/10.5772/intechopen.95736*

[12] Negrini S, Gorgoulis VG,

2010;11(3):220-8.

Elsevier.

2008;9(8):535-41.

mutagenesis. 2014;5.

2014;111(42):15138-43.

Halazonetis TD. Genomic instability an evolving hallmark of cancer. Nature reviews Molecular cell biology.

[13] Ferguson LR, Chen H, Collins AR, Connell M, Damia G, Dasgupta S, et al., editors. Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition. Seminars in cancer biology; 2015:

[14] Abdel-Rahman WM. Genomic instability and carcinogenesis: an update. Curr Genomics.

[15] Yao Y, Dai W. Genomic instability and cancer. Journal of carcinogenesis &

Korolev KS. Tug-of-war between driver and passenger mutations in cancer and other adaptive processes. Proceedings of the National Academy of Sciences.

[16] McFarland CD, Mirny LA,

[17] Barnes JL, Zubair M, John K, Poirier MC, Martin FL. Carcinogens and DNA damage. Biochemical Society Transactions. 2018;46(5):1213-24.

[18] Kaufmann WK, Paules RS. DNA damage and cell cycle checkpoints.

[20] Kowalczykowski SC. An overview of the molecular mechanisms of recombinational DNA repair. Cold Spring Harbor Perspectives in Biology.

Faseb j. 1996;10(2):238-47.

2017;58(5):235-63.

2015;7(11):a016410.

[19] Chatterjee N, Walker GC. Mechanisms of DNA damage, repair, and mutagenesis. Environmental and molecular mutagenesis.

[2] Jeggo PA, Pearl LH, Carr AM. DNA repair, genome stability and cancer: a historical perspective. Nature Reviews

Mostoslavsky R, Franco S, Gostissa M, Alt FW. DNA Repair, Genome Stability, and Aging. Cell. 2005;120(4):497-512.

[4] Darmon E, Leach DRF. Bacterial Genome Instability. Microbiology and Molecular Biology Reviews.

[5] Aunan JR, Watson MM, Hagland HR, Søreide K. Molecular and biological hallmarks of ageing. Br J Surg.

[6] Aunan JR, Cho WC, Søreide K. The Biology of Aging and Cancer: A Brief Overview of Shared and Divergent Molecular Hallmarks. Aging Dis.

[7] Petr MA, Tulika T, Carmona-Marin LM, Scheibye-Knudsen M. Protecting the Aging Genome. Trends in Cell Biology.

[8] Abbas T, Keaton MA, Dutta A. Genomic instability in cancer. Cold Spring Harbor perspectives in biology.

Bennett M. DNA damage and repair in atherosclerosis. Cardiovascular Research. 2006;71(2):259-68.

[10] Wu J, Lu L-Y, Yu X. The role of BRCA1 in DNA damage response. Protein & cell. 2010;1(2):117-23.

[11] Rosen EM. BRCA1 in the DNA damage response and at telomeres. Frontiers in genetics. 2013;4:85.

[1] Edwards AW. The genetical theory of natural selection. Genetics.

2000;154(4):1419-26.

**References**

Cancer. 2016;16(1):35.

2014;78(1):1.

2016;103(2):e29-46.

2017;8(5):628-42.

2020;30(2):117-32.

2013;5(3):a012914.

[9] Mahmoudi M, Mercer J,

[3] Lombard DB, Chua KF,

*Genomic Instability and DNA Repair in Cancer DOI: http://dx.doi.org/10.5772/intechopen.95736*
