**9. Conclusion**

Defects in the repair system assure genomic instability, this fuels disorderliness required for cancer to survive, sustain and evolve; that is why hereditary deficiencies in them makes the individual more susceptible to cancer. There are only some repair genes known to be exploited by cancer, a more extensive search of potential points might give a perspicuous picture. Researchers has been into understanding and finding cure to cancer since decades; but still till date we do not have a conclusion. This refers to its multiple techniques, different hierarchical steps and several process that it applies for its successful survival. DNA repair system is one of its basic targets, so cancer wangle it very well to establish its existence. It applies different mechanism from simple mutations to clustered mutations to various epigenetic changes just to assure a compromised repair system. A very elaborate venture of these changes can give us insight into generation of genomic instability by suppressing DNA repair in cancer. This information can help us get the much-sought effective treatment. Therapies targeting DNA repair genes already available are example to this.
