**6. Acknowledgements**

The authors would like to thank Drs. Henry Pitot and Ruth Sullivan for liver histopathology training and diagnoses. We thank Bradley Stewart (McArdle) for microarray processing and the Lab Animal Resources technicians for animal care. We thank Christopher Oberley for reading the manuscript and Matt Gigot, Kim Luetkehoelter, Tonia Jorgenson, Manching Leung, Heather Sturm, Katie Halser, Carl Koschmann, Henri Kurniawan, Jessica Linzmeyer, Myrra Windau, Fatima Ashraf, Bridget Borg, and Eric Simpson for their contributions. This work was supported by grants from the U.S. National Institutes of Health (CA22484, CA96654, CA07175, CA09135, and CA14520).
