**4.5 Ultrasound monitoring of post-surgical resection status**

Surgical resection is the treatment of choice for non-cirrhotic or cirrhotic patients with well preserved liver function with single liver lesion. After resection, recurrence rate exceeds 70% at 5 years and is mainly due to primary tumor dissemination. The strongest predictors of tumor recurrence are the development of other tumors near the primary tumor scar and vascular microinvasion (Bruix & Sherman, 2005). 2D ultrasound is used within screening programs. CEUS efficacy has not been proven so far in monitoring postresection patients.
