**9. Acknowledgement**

We thank associate professor Akinobu Shimizu of Tokyo University of Agriculture and Technology for providing liver region extract program. We also thank JAMIT and MICCAI for providing CT images. This work was supported in part by the Grant-in Aid for Scientific Research from the Japanese Ministry for Education, Science, Culture and Sports under the Grant No. 21300070 and 22103513, and in part by the Research fund from Ritsumeikan Global Innovation Research Organization (R-GIRO). Wei Xiong and Jiayin Zhou acknowledge supports from Singapore A\*STAR project JCOAG03\_FG05\_2009.
