**Abstract**

Lately, a brand-new studies agenda emphasizing interactions between societal elements and wellness has emerged. The phrase social determinant of health and fitness typically refers to any nonmedical element directly effecting health, including behaviors, knowledge, attitudes, and values. Status of health is adversely and strongly impacted throughout the life span by social disadvantages. Epigenetic mechanisms are implicated in the processes through which social stressors erode health in humans and other animals. Research in epigenetics suggests that alterations in DNA methylation might offer a temporary link between interpersonal adversity and wellness disparity. Likewise, accelerated loss in telomeres is extremely correlated not only with chronic and social stress but also aging. Therefore, it may provide a link between the various physiological events associated with health inequalities. Research in epigenetics indicates that alterations in DNA methylation may provide a causal link between social adversity and health disparity. Additionally, these experimental paradigms have yielded insights into the potential role of epigenetic mechanisms in mediating the effects of the environment on human development and indicate that consideration of the sensitivity of laboratory animals to environmental cues may be an important factor in predicting long-term health and welfare.

**Keywords:** stress, epigenetic, DNA, social, environment
