**6. Wheat computational analysis**

A comprehensive resource for wheat reference genome was developed by International Wheat Genome Sequencing Consortium. The URGI portal (https:// wheat-urgi.versailles.inra.fr/) was developed for the breeders and researchers to access the genome sequence data of bread-wheat. InterMine tools, genome browser, and BLAST were established for the exploration of genome sequences together with the additional linked datasets, including gene expression, physical maps, and sequence variation. Portal provided the higher browser and search features that facilitated the use of the latest genomic resources required for the upgradation of wheat [65].

DNA binding with one finger (Dof) transcription factors is known to have an important role in abiotic stress tolerance as well as the growth of plants. Ninetysix TaDof members of the gene family have been studied using computational approaches. By qPCR analysis, it was revealed that TaDof genes were upregulated under heavy metal and heat stress in wheat. Consequently, it could be concluded that detection of amino acid sites, genome-wide analysis, and identification of the Dof transcription factor family could provide us the new insight into the function, structure, and evolution of the Dof gene family [66].
