**10. Conclusion**

During OLT it is possible to maintain coagulation competence by timely administration of fresh frozen plasma and platelets together with SAGM-blood while body temperature and plasma pH and calcium are controlled. Notably platelets are supplemented to a reference value of 100 X 109 L-1 rather than 50 X 109 L-1 seems to increase survival. Even massive bleeding can be coped with if CBV and thereby ScO2, at all times is kept within narrow limits. To maintain a stable central blood volume requires that treatment of patients with liver disease is focused on eventually high maximal values for CO and SvO2.
