**3. Liver transplantation**

As previously noted, advances in critical care management of ALF patients has improved the spontaneous survival from 10-20% to about 40% without transplantation (Ostapowicz et al., 2002). For those who will not spontaneously recover; however, OLT remains the only treatment modality that improves survival. With the advent of use of OLT in this setting, overall survival rates have further improved to about 60%.
