**2.1 Incidence and prevalence**

In North America and Europe, the incidence of MH is currently estimated to be 1:15,000 anesthetics for children and adolescents and 1:50,000–1:150,000 anesthetics for adults21-23. The prevalence for this syndrome in the general population is unknown because of lack of universal reporting, but although it may be as common as one in 200024. Malignant hyperthermia is more common in male patients25. The incidence and prevalence varies from country to country, based on differences in gene pools26-30.

Although the incidence of reported episodes of MH has increased, the mortality rate from MH has declined. This may reflect a greater awareness of the syndrome, earlier diagnosis, and better therapy31.
