**5. Conclusion**

*P. aeruginosa* ability to easily colonize in host, biofilm formation, synthesis and secretion of virulence factors and causing pathogenicity, evading host immune defense system, and antimicrobial resistance made it a critical pathogen and needs an immediate attention. Secretion of extracellular molecules by *P. aeruginosa* plays a principal role in fitness of bacterial population, establishment of biofilms, infections, and pathogenicity in host. To reduce and eradicate *P. aeruginosa* associated infections development of novel antibiotics or antimicrobial agents, QS inhibiting molecules, virulence factor neutralizing agents, biofilm disrupting enzymes or/and combination treatment strategy with existing antimicrobial agents are of top priority. Further to prevent antimicrobial resistance in bacteria, necessary steps need to be taken by government organization, hospitals/clinics, health care workers and scientist from research institutes to educate children and students in schools, colleges and universities, people from rural places and developing countries about proper hygiene and use and misuse of antibiotics. Also, proper management of antibiotics uses in the agriculture and meat industry need to be implemented. This small steps at every level will help in minimize the spread of antimicrobial resistance in bacteria and will help to cut down catastrophe in both health and economic division and promotes better treatment outcome against infectious diseases.
