**6. Conclusion**

Our current knowledge and understanding of the specific role of gender in the context of periodontal health status remain limited and need further elucidation. The combined effect of sex-specific genetic architecture and the circulating levels of sex steroid hormones may account for variation in risk for chronic periodontitis, with men exhibiting greater susceptibility than women. The preliminary case study presented here revealed age as a significantly associated factor, with the total number of bone loss sites and with the bone loss site extended up to a middle third of tooth root (moderate to severe periodontitis cases), but could not delineate gender, the primary factor being explored as a clear-cut risk factor, owing to the lack of statistical strength and study limitations as the small-sized sample, retrospective study design. This shall not obviate the need to explore this factor as a cause of concern as contemporary models of periodontal pathogenesis; differences in susceptibility, and progression of destructive periodontal disease are attributed to the individual and collective biologic and modifiable risk factors. With this framework
