**Abstract**

This literature review will aim to recapitulate the different factors involved in the endodontic regenerative procedure, with a focus on different bacterial disinfecting techniques, intra-canal dressings and expected treatment outcomes. The electronic databases searched were EMBASE, MEDLINE and PUBMED. Articles included were limited to the English language from the year 1988 to May 2019. A hand search of the literature was also performed for articles dating back to 1958. No clear guidelines were available regarding follow-up and expected treatment outcomes in terms of success, survival (acceptable) or treatment failure. However, calcium hydroxide as an intra-canal medicament was found to be the best treatment modality in comparison to antibiotic paste for intra-canal dressing.

**Keywords:** regeneration, endodontics, dentistry, necrotic pulp
