**1. Introduction**

Aortic valve disease is common in the elderly people. In clinical practice, many elderly patients, as well as patients with other organ dysfunctions, cannot tolerate the valve replacement surgery of open chest with cardiopulmonary bypass. Transcatheter aortic valve implantation (TAVI) technology can complete valve replacement without thoracotomy, cardiac arrest, and cardiopulmonary bypass. Its advantages are obvious. This chapter will review the research and development history of TAVIi technology and different design features of TAVI valve, especially the application effect of Chinadesigned TAVI valves in China. What's more, TAVI technology brings not only technological innovation, but also a new team cooperation mode for disease treatment, which can better provide heart valve disease patients with higher quality and safer tsreatment. Finally, in addition to the aortic stenosis, earliest indications of TAVI, it can also be used for the treatment of aortic valve regurgitation. The new generation of TAVI valve has a unique design helpful in leaflets fixation and clamping, which can complete the interventional treatment easily.
