**Abstract**

The growing number of electronic intracardiac devices (pacemakers, resynchronizers and defibrillators) and non-electronic devices (percutaneous occluders) implanted, combined with certain common characteristics in the treated population (underlying heart disease, advanced age, kidney disease, multiple associated pathologies), have led to a change in the spectrum of presentation of endocarditis, with an increase in cases related to these devices. These infections pose diagnostic and therapeutic challenges due to the complexity of the patients, the microorganisms involved –who frequently generate the formation of biofilmand the percutaneous or surgical techniques involved in the removal of material. All these circumstances require a multidisciplinary approach.

**Keywords:** endocarditis, cardiac implantable electronic device (CIED), infection, biofilm, prophylaxis
