**Author details**

Vira I. Ayzenbart and Mark Joseph\* Virginia Tech Carilion School of Medicine, Roaonke, Virginia, USA

\*Address all correspondence to: mjoseph@carilionclinic.org

© 2021 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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