**1. Introduction**

Advances in treatment have led to improved survival of patients with cancer but have also increased morbidity and mortality due to treatment side effects [1, 2]. Chemotherapy and radiation therapy can put patients at risk for a variety of cardiovascular complications including heart failure, coronary artery disease, peripheral vascular disease, thromboembolism, pericardial disease and valvular heart disease. Cardiovascular disease is now the second leading cause of morbidity and mortality in cancer survivors [3]. Cancer patients receiving therapy with known cardiac risk require close monitoring during and after treatment. In current cardio-oncology practice, echocardiography is the most widely used technique in the diagnosis, prevention and risk stratification of CTRCD in patients during and after cancer therapy. The utility of the advanced echocardiography is emerging as the threedimensional echocardiography derived left ventricular ejection fraction (LVEF) has an excellent correlation with cardiac magnetic resonance imaging and can be used to monitor LVEF and the two-dimensional speckle tracking echocardiography

(2D-STE) derived strain and strain rate can detect changes in myocardial mechanics before changes in LVEF occur.
