**4. Analysis of guidelines for AMI treatment**

Both the AHA-ACC guidelines and the ESC guidelines for AMI treatment are strongly oriented to early and sustained reperfusion, which constitutes the most powerful resource for improving prognosis and saving lives during the event. The best way to show successful post-PCI or thrombolytic reperfusion is to verify the correction of the ST segment of the ECG performed after reperfusion therapy. Approximately 30% of patients receiving primary angioplasty in a timely manner do not correct ST elevation or initially correct it but continue to lose positive ECG vectors after apparently successful reperfusion. As we saw in the previous section, this happens because there is myocardial damage before, during, and after reperfusion [53]. However, the analysis of the guidelines shows that measures to reduce myocardial damage beyond reperfusion are poorly developed. The related items found in the current guides are reproduced below.
