**Meet the editor**

Dr. P. Syamasundar Rao is a Professor of Pediatrics and Medicine and Emeritus Chief of Pediatric Cardiology at the University of Texas-Houston Medical School and Professor of Pediatrics at the University of Texas M.D. Anderson Cancer Center in Houston, Texas, USA. Dr. Rao received his medical degree from Andhra Medical College/University in Visakhapatnam, India. He re-

ceived training in Pediatric Cardiology at Stanford University, Case-Western Reserve University, and University of California in Los Angeles. After training, he joined the faculty at the Medical College of Georgia in Augusta, Georgia, USA, and became the Associate Director of Pediatric Cardiology. His subsequent positions were as follows: Consultant Pediatric Cardiologist and Chairman, Department of Pediatrics, King Faisal Specialist Hospital and Research Center in Riyadh, Saudi Arabia, Professor and Director of Division of Pediatric Cardiology at the University of Wisconsin in Madison, Wisconsin, and Professor/Director of the Division of Pediatric Cardiology at Saint Louis University School of Medicine/Cardinal Glennon Children's Hospital, St. Louis, Missouri. Dr. Rao authored 350 papers, eight monographs/books, and 55 book chapters. He lectured and made catheter intervention demonstrations in a number of countries including India, USA, Australia, Finland, Sweden, Germany, New Zealand, Brazil, and Japan.

Contents

**Preface IX** 

**Part 1 Overview of Congenital Hear Defects 1** 

**of Congenital Heart Diseases 47**  Jarun Sayasathid, Kanchapan Sukonpan

Susumu Minamisawa and Utako Yokoyama

Chapter 4 **Bone Morphogenetic Protein Signaling Pathways in Heart Development and Disease 97** 

Cristina Harmelink and Kai Jiao

**of Congenital Heart Disease 121**  Jing-bin Huang and Jian Liang

Chapter 6 *Drosophila* **Model of Congenital Heart Diseases 141**  Georg Vogler, Rolf Bodmer and Takeshi Akasaka

> **Transposition of the Great Arteries 161**  English C. Flack and Thomas P. Graham

**Molecular Mechanism of Patent Ductus Arteriosus 85** 

Chapter 1 **Congenital Heart Defects – A Review 3** 

P. Syamasundar Rao

**Part 2 Prevalence and Etiology 45** 

and Naraporn Somboonna

Chapter 3 **Recent Advances Concerning the** 

**Part 3 Individual Heart Defects 159** 

Chapter 2 **Epidemiology and Etiology** 

Chapter 5 **Molecular Mechanisms** 

Chapter 7 **Congenitally Corrected** 
