**3.4 Myocardial redox state or anaerobic metabolism (Table 3)**

The lactate/pyruvate (L/P) ratios in coronary vein were similar among the groups. However, the L/P ratios of both ASD group and PH group were relatively higher values than those of KD group. Each values of redox potential (Eh) calculated from blood lactate and pyruvate showed no significant difference among groups. The ΔEh also showed no significant difference among the groups but the ΔEh of PH group was relatively lower value than other groups.

#### **3.5 The effects of oxygen inhalation**

As some patients in PH group were supposed myocardial relative ischemia or hypoxic state, we measured the major energy substrates under administration of oxygen for CHD patients. Figure 2 demonstrates the change of lactate OER both from ASD group and PH group. Lactate OER of ASD group did not change with oxygen inhalation. On the other hand, its PH group increased from -6.3±10.9% to 3.0±9.9%. However, of interest, both the CS L/P ratio and ΔEh of each group showed no remarkable changes even after inhale of oxygen (Table 3).
