**4. Conclusion**

Staphylococcus is an adaptable pathogen and has ability to develop rapid antibiotic resistance. After 1980s development of newer classes of antibiotics is very limited. Rapid development of resistance will reduce the availability of antibiotic in clinical practice and this will cause serious health problem in future. Development of newer molecules in expensive clinical trials, the huge investment in target based discovery with the structural biology did not yield the hope for newer break throughs. Microorganisms are very crucial in developing resistance to novel therapeutic agent rapidly. This will development of more strategies to combat the antibiotic resistance. Antibiotic stewardship policy is mandatory to control the development and spread of antibiotic resistance in community and hospital settings.

*Insights Into Drug Resistance in* Staphylococcus aureus
