**5.3 Veterinary and medicinal cost**

The veterinarian cost for treatment fee, travel and labor charges. On an average a handsome expenditure of \$444 in clinical mastitis case are charged. This include (128\$) directly in term of diagnostic (10\$), medicinal expenditure (\$36), discarded milk (\$25), Veterinary charges (\$41), extra labor (\$4) while death losses (\$32). The indirect costs are (\$316) which include (\$125) through future production losses and (\$182) for culling and replacement and whereas reproductive losses are (\$9). Therefore, to take an accurate decision to control the mastitis depends on understanding of economic impact of mastitis [43, 53]. Mastitis is among the main reason in cattle for the use of antibiotics and this exposure of animal to antibiotics is main reason behind the development of antibiotic resistant bacteria and antimicrobial residues in milk which are of a great public health concern [4, 7].
