**2. Clinical aspects of liver transplantation**

From a clinical point of view, the outcome of transplantation depends on the general condition of the recipient (MELD score in adults and PELD score in children) before surgery and the quality of the graft, surgical technique, postoperative care, immunosuppressive therapy. The operation is one of the largest in volume and complexity in surgery in general. Most often in Europe and the United States the so-called "standard" LT is performed, in which an entire organ is transplanted - whole liver graft. Deceased liver transplantation (DLT) is not common in Asia and part of a living donor organ is used [4, 5].

In deceased, an organ donation is possible when the graft is from a donor who has been registered as brain dead (brain dead donor) and donation after cardiac death.

Liver transplantation from a living donor (LDLT) offers some advantages over cadaveric donation: determining the time of the operation, the graft is from a healthy person and is in optimal condition, the cold ischemia time is shortened. It is suitable for children due to the possibility of precise selection of the graft in
