**5. Conclusion**

Clinical trials developed by American researchers involving COVID-19 include adult and elderly participants, with predominance of randomized, parallel and open design, those for therapeutic purposes and those that mostly evaluate immunosuppressants or combinations of antivirals/immunosuppressants. The drugs and biological products Remdesivir, Baricitinib in combination with Remdesivir, Bamlanivimab and Etesevimab, REGEN-COV and COVID-19 convalescent plasma were also used, authorized for emergency use.
