**10. Clinical trial status**

The process of systemic review was followed and effectiveness of the drug analyzed from the NIH, US National Library of Medicine Clinical Trial Registry (ClinicalTrials.gov). At present (till May 2021), 81 clinical studies could be traced in the name Toclilizumab [until May 2021]. 33 studies have been excluded due to nonrelevance. 48 records are included in this study. Some of the studies have yielded promising initial results yet require more time for validation and declared to be effective or safe. Among the 48 trials done on Tocilizumab, 17 are in Recruiting stage, 12 trials have been concluded, 5 have been terminated, 1 has been withdrawn, 5 trials are in not yet recruiting stage and 6 are active but non recruiting. 1 among the 47 trials is in phase 1, 16 trials are in phase 2, 14 are in phase 3 trial. Analyzing the clinical trials from **Table 1**, it is evident that there is attempt to use Toclizumab alone or in combination with other drugs looks promising for the treatment of COVID 19 (**Figure 1**).
