*3.5.6 Prognosis*

The perinatal HPP is often lethal within days if not weeks after birth with approximately 50% of the affected infants succumbing to respiratory complications. Report on prolonged case survival was lacking for infantile or childhood HPP. Patients affected by adult HPP or odontohypophosphatasia, on the other hand, were expected to enjoy a normal lifespan [71, 72, 75].
