*3.5.5 Genetic counseling*

Severe forms of HPP (perinatal and infantile) are inherited via an autosomal recessive fashion, while milder HPP appears to transmit in autosomal recessive or autosomal dominant manner. The risk of severe HPP recurrence therefore, is considered at around 25% while moderate HPP transmission could be 25% (recessive transmission), 50% (dominant transmission) or varying (usually <50%) due to the variable expressivity of dominant HPP forms [71, 72].
