**4. Conclusion**

Periodontal disease and especially periodontitis are often the major clinical characteristic of these genetic disorders. In light of the fact periodontal disease may be the first detectable sign of an undiagnosed genetic disorder and/or indicator for the latter's activity progression, oral health professions shall acquire essential knowledge and be cognizant regarding the rare occasions that these diseases could be encountered. In this chapter, we discussed some genetic disorders associated to periodontal disease, we hope this work can help dental practitioners to be familiar with these genetic disorders and their negative impacts on the periodontal tissues hence poor oral/periodontal health of the affected.
