*2.4.5 Miscellaneous activities*

The insect repellent activity of EOs is well studied and many research papers have been published. The EOs of *Hyptis spicigera* Lamarck and *Hyptis suaveolens* (L) Poitier and *Lavandula angustifolia* (Miller) showed repellent activity on *Sitophilus zeamais* adults [114].

EOs of the leaves of *Endlicheria bracteolate* was tested against *Leishmania amazonensis* by Rottini and collaborators. The antileishmanial activity was evaluated against promastigotes and intracellular amastigotes, and cytotoxicity was performed with J774.G8, which were incubated with different concentrations of *E. bracteolate*. Promastigote forms showed *E. bracteolate* EO IC50 value of 7.945 μg/mL (24 h). The IC50 value was 15.14 μg/mL showing that *E. bracteolate* EO is less toxic to macrophages than to parasites [115].
