**2. Methods**

This trial was an open-label, randomized, clinical trial which enrolled 315 patients undergoing coronary artery bypass grafting with arteries (internal mammary, radial, gastroepiploic) or inverted saphenous veins in a single center (Cardiac Surgery Department of "Prof. Dr. C. C. Iliescu" Emergency Institute of Cardiovascular Diseases, Bucharest, Romania) between January 1st, 2006 and December 31st, 2007. Surgical management and treatment of the patients were based on a common standard protocol.
