**6. Acknowledgements**

Authors want to thank the cardiac surgery team of the Virgen del Rocío University Hospital. Their support and interest in Immunology research have been critical for us. Similarly, we are thankful to Dr. Felipe Borderas and the Service of Anatomical Pathology of the HUVR as key help with H&E slides preparation and interpretation. This work has been supported by Red de Investigación en SIDA (ISCIII RETIC RD06/0006/0021 and RD06/0006/0035).
