**1. Introduction**

108 Perioperative Considerations in Cardiac Surgery

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ischemic preconditioning: a novel protective method from ischemia reperfusion

Pulmonary hypertension (PH) was first described over 100 years ago, but a thorough understanding of its pathogenesis and a successful approach to curing the disease still remain under investigation.

Advanced research in the field of PH has enhanced our understanding of this entity and has led to new therapies. PH is rare but can affect people of all ages and is associated with several seemingly unconnected diseases.
