Meet the editor

Professor Doctor Ali Gamal Al-kaf has a PhD in Pharmaceutical Sciences from the Chief Council for Accreditation and Quality Assurance, Russia (2006). Previously he has been Dean of Faculty of Pharmacy at Sana'a University, Professor of the Medicinal Chemistry Department, member of the Yemeni Medical Council, and a member of many associations and international groups. He is executive editor of the *Universal Journal of Pharmaceutical Research*, and editor and

associate editor of a number of international journals. His interests are the synthesis and biological activity of 4-oxopyrimidine and quinazolinone-4 derivatives, structural biology and bioinformatics in drug design, study of Yemeni medicinal plants, development and validation of spectrophotometric and HPLC methods for different drugs, and antibiotic and antimicrobial resistance in Yemen. .He is the author of more than 70 publications, four patents, and 11 books.

Contents

**Section 1**

**Section 2**

and Quinazoline Derivatives

Biological Activity of Quinazolinones *by Awwad A. Radwan and Fars K. Alanazi*

*by Ali Gamal Al-kaf*

*by Heba E. Hashem*

*by Samir Y. Abbas*

Biological Application *by Satyendra Mishra*

*Ileana Cornelia Chiriţă*

**Preface III**

The Newest Research in Quinazolinone and Quinazoline Derivatives **1**

**Chapter 1 3**

**Chapter 2 11**

Synthesis and Biological Activity **39**

**Chapter 3 41**

**Chapter 4 53**

**Chapter 5 75**

**Chapter 6 91**

*by Cornel Chiriţă, Carmen Limban, Diana Camelia Nuţă, Emil Ştefănescu,* 

*Oana Cristina Șeremet, Mihaela Trandafir (Bratu), Alexandru Vasile Missir and* 

*Simona Negreş, Cristina Elena Zbârcea, Cristina Daniela Marineci,* 

Introductory Chapter: The Newest Research in Quinazolinone

Synthesis of Quinazoline and Quinazolinone Derivatives

Quinazolinone and Quinazoline Derivatives: Synthesis and

Synthesis and Pharmacological Research Regarding New

Compounds with Quinazolin-4-One Structure

Chemical Reaction, and Biological Properties

4(3*H*)-Quinazolinone Derivatives: Syntheses, Physical Properties,
