Contents


Preface

Noncoding RNAs (ncRNAs) have made a huge impact on RNA biology. ncRNAs play important roles in regulating gene expression in animals, plants, and various human diseases. This book provides an overview of current knowledge on ncRNA research by dealing with miRNA- and ncRNA-related human diseases, plant miRNA markers, and the roles of lncRNAs in cancer and epigenetics. The book starts with a brief introductory chapter on ncRNAs. The second chapter discusses the pathogenetic role of miR-335-5p in gastrointestinal tumors. The third chapter focuses on miRNA expression in smoking-induced periodontitis. The fourth and fifth chapters describe the role of herpesvirus-encoded miRNAs in avian diseases and the role of three miRNA families in the progression of skin aging. The sixth chapter covers miRNA-based markers in plants and their application in plant genotyping. The seventh chapter elaborates the role of ncRNAs, especially circRNAs, miRNAs, mRNAs, and their interactions, in brain cells. The last two chapters review lncRNAs as hallmarks of cancer with clinical applications and their functions as epigenetic regulators. Overall, the book content provides a unique perspective to scientists in

> **Dr. Lütfi Tutar** Assistant Professor,

> > Kırşehir, Turkey

**Dr. Sümer Aras** Professor,

**Dr. Esen Tutar** Assistant Professor,

Kırşehir, Turkey

Ankara University, Ankara, Turkey

Kırşehir Ahi Evran University,

Kırşehir Ahi Evran University,

the field.
