*6.2.6 Ischemic preconditioning*

Ischemic preconditioning includes exposure to short episodes of ischemia followed by reperfusion to make the target organ prepared against the main ischemic insult. If the site of generation of these short episodes of ischemic reperfusion is remote from the site of target organ, it is called remote ischemic preconditioning. This technique has been used with only variable success in offering myocardial and renal protection in cardiovascular medicine [145–151]. Results of an RCT propose usefulness from remote ischemic preconditioning in preventing CIN [152]. The likely usefulness may arise from its capability to attenuate the CM-induced ischemia reperfusion injury. Recently, ischemic preconditioning has lost its credibility as it was unable to translate successful results in laboratories into clinical practice [153].
