**6.2 Amlodipine**

Similar to second-generation dihydropyridines, it has a higher selectivity for the vascular smooth muscles than the myocardial tissue. It has a longer half-life (34 hours) but less negative inotropic effect than nifedipine. It is used in the treatment of chronic stable angina and essential hypertension [7]. Amlodipine increases exercise duration, decreases anginal attacks, and reduces the consumption of **nitroglycerin.** It is given once daily (at a dose of 5 or 10 mg). Common side effects of the dihydropyridines are less likely with amlodipine**.**
