**2.2 Acute myeloid leukemia**

In general, patients with AML have similar signs and symptoms as patients with ALL which mainly includes symptoms related to (pan)cytopenia. AML is the most common acute leukemia in adults, whereas it is relatively rare in children (accounting for only 10% of the acute leukemia) [15]. Overall, AML occurs in 3–5 cases per 100.000 people, and the incidence strongly increases with age.
