**Author details**

Fieke W. Hoff<sup>1</sup> \* † , Anneke D. van Dijk1† and Steven M. Kornblau<sup>2</sup> \*

1 Department of Pediatric Oncology/Hematology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

2 Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA

\*Address all correspondence to: f.w.hoff@umcg.nl and skornblau@mdanderson.org

† These authors contributed equally to the work.

© 2019 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

**75**

**122**(10):3398

*Proteoforms in Acute Leukemia: Evaluation of Age- and Disease-Specific Proteoform Patterns*

47-60

lymphoblastic leukemia. Pediatric Clinics of North America. 2015;**62**(1):

[11] Pieters R, Schrappe M, De Lorenzo P, Hann I, De Rossi G, Felice M, et al. A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia

(Interfant-99): An observational study and a multicentre randomised trial. The

Kamps W, et al. Outcome of treatment in childhood acute lymphoblastic leukaemia with rearrangements of the 11q23 chromosomal region. The Lancet.

[13] Hunger SP, Loh ML, Whitlock JA, Winick NJ, Carroll WL, Devidas M, et al. Children's Oncology Group's 2013 blueprint for research: Acute lymphoblastic leukemia. Pediatric Blood

Lancet. 2007;**370**(9583):240-250

[12] Pui C, Gaynon PS, Boyett JM,

Chessells JM, Baruchel A,

2002;**359**(9321):1909-1915

& Cancer. 2013;**60**(6):957-963

[14] Rubnitz JE, Lensing S, Zhou Y, Sandlund JT, Razzouk BI, Ribeiro RC, et al. Death during induction therapy and first remission of acute leukemia in childhood: The St. Jude experience. Cancer. 2004;**101**(7):1677-1684

[15] Siegel RL, Miller KD, Jemal A. Cancer statistics, 2017. CA: A Cancer Journal for Clinicians. 2017;**67**(1):7-30

[16] Arber DA, Orazi A, Hasserjian R, Thiele J, Borowitz MJ, Le Beau MM, et al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia.

[17] Bullinger L, Döhner K, Döhner H. Genomics of acute myeloid leukemia diagnosis and pathways. Journal of Clinical Oncology. 2017;**35**(9):934-946

Blood. 2016;**127**(20):2391-2405

*DOI: http://dx.doi.org/10.5772/intechopen.90329*

[1] Inaba H, Greaves M, Mullighan CG. Acute lymphoblastic leukaemia. The Lancet. 2013;**381**(9881):1943-1955

Bloomfield CD. Acute myeloid leukemia. The New England Journal of Medicine.

Darmanis S, Prakadan SM, Ziegler CGK, et al. Multiplexed, targeted profiling

[2] Döhner H, Weisdorf DJ,

[3] Genshaft AS, Li S, Gallant CJ,

[4] Payne SH. The utility of protein and mRNA correlation. Trends in Biochemical Sciences. 2015;**40**(1):1-3

[5] Vogel C, Marcotte EM. Insights into the regulation of protein abundance from proteomic and transcriptomic analyses. Nature Reviews. Genetics.

[6] Katz AJ, Chia VM, Schoonen WM, Kelsh MA. Acute lymphoblastic leukemia: An assessment of international incidence, survival, and disease burden. Cancer Causes & Control: CCC. 2015;**26**(11):1627-1642

[7] Iacobucci I, Mullighan CG. Genetic basis of acute lymphoblastic leukemia.

Journal of Clinical Oncology.

[8] Boissel N, Baruchel A. Acute lymphoblastic leukemia in adolescent and young adults: Treat as adults or as children? Blood. 2018;**132**(4):351-361

[9] Van Vlierberghe P, Ferrando A. The molecular basis of T cell acute lymphoblastic leukemia. Journal of Clinical Investigation. 2012;

[10] Bhojwani D, Yang JJ, Pui CH. Biology of childhood acute

2017;**35**(9):975-983

of single-cell proteomes and transcriptomes in a single reaction. Genome Biology. 2016;**17**(1):188

2012;**13**(4):227-232

2015;**373**(12):1136-1152

**References**

*Proteoforms in Acute Leukemia: Evaluation of Age- and Disease-Specific Proteoform Patterns DOI: http://dx.doi.org/10.5772/intechopen.90329*
