**6. Conclusion**

In conclusion, the proteoform identification using a proteomic approach can be an advance in diagnostic routines and development of precision/personalized medicine. Efforts should be concentrated on clinical studies and then on, and one aspect that precludes is the cost and complexity of these tests. Therefore, studies to simplify sample preparation steps and MS platforms need to be performed to reduce cost per test.

**19**

**Author details**

Jucélia da Silva Araújo and Olga Lima Tavares Machado\*

\*Address all correspondence to: olga@uenf.br

provided the original work is properly cited.

Universidade Estadual do Norte Fluminense-Darcy Ribeiro, Rio de Janeiro, Brazil

© 2019 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium,

*Proteoforms: General Concepts and Methodological Process for Identification*

*DOI: http://dx.doi.org/10.5772/intechopen.89914*
