**7. Conclusions**

Disintegration of microorganisms in bead mills is the process of random transformation of organic matter dispersed in limited space. The general theory can be used to formulate a phenomenological model of the disintegration process and its mathematical description. They allow us to illustrate fundamental phenomena and mechanisms of the tested process. The presented method of modeling allows us to analyze many factors that have an influence on the kinetics of transformations, for instance such as different sizes, strength and morphological forms of cells.

The disintegration of microorganisms covers the process of cell disruption and subsequent release of intracellular compounds contained in the cells. The discussed results of experiments proved that the size of cells of microorganisms of the same species had an effect on microorganism disintegration rate. A subsequent loss of the biggest size fractions during the process causes nonlinearity of cell disruption kinetics. The probability of decay of the biggest cell size fractions at a very low concentration of microorganisms is very high. It decreases with an increase of the concentration of microbial suspensions.

In the packing of the mill working chamber, with an increase of the suspension concentration increases also intensity of intercellular relations due to filtering of microorganisms in the space which is safe for them. At high and very high concentrations, cells deformed due to compression can force out adjacent cells from the destruction zone causing a decrease of the process rate at its initial stage. An increase of the rates of cell disruption and release of intracellular compounds at medium and high concentration of microbial suspensions can be caused by mutual blocking of cells, blocking of cells by fragments of disintegrated microorganisms or the interaction of released intracellular compounds. Results of the discussed investigations confirmed the dependence of compound release rates on the position of these compounds in a cell.
