*7.4.1 Clinical phase I*

The first phase of clinical trial normally takes several weeks to some months. At this stage application of optimized drug is tested on a small group of volunteers.

**Figure 6.** *The journey of potential leads from preclinical to clinical trials.*

They may or may not get paid for their participation in drug trial studies. This mini trial is useful in determining the absorption and side effect of drug in relation to its dose concentration [17].
