Meet the editor

Dr. Belakatte Parameshwarappa Nandeshwarappa holds an M.Sc. and Ph.D. from Kuvempu University, Karnataka, India. He was a Postdoral fellow at the Institute of Fine Chemicals, East China University of Science and Technology, Shanghai. He has published many scientific papers in peer-reviewed journals and presented his research papers at national and international conferences, seminars and workshops. He has edited five books,

authored seven specialized books and five book chapters. His main areas of research are organic synthesis, process developments, and medicinal chemistry. He has guided fifty-one dissertation theses for postgraduate students and is currently guiding Ph.D. students. He has fourteen years of teaching experience and three years of industry experience. Dr. Belakatte Nandeshwarappa received several awards such as young scientist, best poster presentation award in recognition for his outstanding contribution to education and research. He is currently working as an Asssociate Professor at DOS in the Chemistry Department, Davangere University, Davangere.

Contents

**Section 1**

Activation

Natural Products

**Section 2**

**Preface III**

Section A **1**

**Chapter 1 3**

**Chapter 2 15**

**Chapter 3 27**

**Chapter 4 51**

**Chapter 5 71**

Section B **105**

**Chapter 6 107**

**Chapter 7 125**

Design and Strategic Synthesis of Some β-Carboline-Based Novel

Synthesis of s- and p-Element Organosiloxanes by Mechanochemical

*by Vitaliy Viktorovich Libanov, Alevtina Anatol'evna Kapustina* 

Approaches to the Total Synthesis of Puupehenone-Type Marine

*by Andivelu Ilangovan, Sakthivel Pandaram and Tamilselvan Duraisamy*

Recent Advances in Mechanochemical Organic Synthesis

*N,N*-Dialkyl Amides as Versatile Synthons for Synthesis

C▬H Activation Strategies for Heterofunctionalization

and Heterocyclization on Quinones: Application in the Synthesis

*by Andivelu Ilangovan and Thumadath Palayullaparambil Adarsh Krishna*

Natural Products of Biological Importance

*by Tejpal Singh Chundawat*

*and Nikolay Pavlovich Shapkin*

*by Davor Margetić and Vjekoslav Štrukil*

of Heterocycles and Acyclic Systems

Synthetic Studies of Vitamin B12

*by David Joshua Ferguson*

of Bioactive Compounds

*by Yan-Chao Wu, Yun-Fei Cheng and Hui-Jing Li*

## Contents



Preface

Organic synthesis remains one of the frontier challenges in organic chemistry and drives quite an active area of research. It usually refers to a process not involving the

The development of new synthetic methods for the preparation of organic molecules continues to be an active and exciting area of research in organic chemistry. The discovery and application of new and interesting methods in organic synthesis is vital to the goals of designing shorter, more elegant, and ultimately more reliable syntheses of novel heterocycles and natural products. Organic synthesis is the complete chemical synthesis of a complex molecule, very often organic molecules, from simple, commercially available precursors. As a scientific discipline, these kinds of synthesis have their formative roots in organic chemistry. The synthesis of heterocycles continues to be one of the most fascinating and well-studied areas of organic chemistry. The book 'Organic Synthesis - A Nascent Relook' is a compendium of recent progress in all these aspects of synthetic chemistry. Herein special emphasis is given to synthesis of various bioactive heterocycles. Careful selection of various topics in this book will serve the rightful purpose for the chemistry community and the industrial houses at all levels, particularly on novel methods developed by the

In organic synthesis, heterocyclic molecules are fundamental building blocks of biological systems. We know that more than 90% of new drugs contain heterocycles and these are the interface between chemistry and biology. These compounds are

This book will serve as reference material for many researchers working in the field of medicinal chemistry, organic chemistry, and pharmaceutical chemistry. Many new synthetic methods for the preparation of organic molecules bare included in this book. Due to their great importance, the development of novel synthetic methods remains an active research area. Therefore, the present book project explores all the new research and developments in synthetic organic chemistry. This book will

**Belakatte Parameshwarappa Nandeshwarappa**

Davangere University,

India

aid of biological processes.

respective authors and their research groups.

inextricably woven into the life processes.

be extremely helpful for all organic chemistry researchers.
