**6. Conclusion**

MicroRNAs (miRNAs) could be used as potential tool for early detection of cancer. It may upregulate or downregulate multiple targets through various mechanisms. It is upregulated as an oncogene (miRNA) and downregulated as a tumor suppressor. microRNA targets the PTEN, interferon (tumor suppressor genes), and *MicroRNA: A Signature for Cancer Diagnostics DOI: http://dx.doi.org/10.5772/intechopen.90063*

also to the cell cycle along with the regulation of these genes [172]. MicroRNA is of vital importance because of its resistance to degradation and could be a potential candidate for clinical applications. However, its expression level can be screened in the serum/plasma (blood) by high-throughput sequencing technology. Further research for identification of novel microRNA will warrant the development of microRNA-related cancer prognosis [176–180].
