**3.7 Type 7 FPLD (FPLD7) and CAV1**

FPLD7 (OMIM #606721) is also caused by the mutation in the *CAV1* gene on chromosome 7q31. Different from the CGL3 that is caused by homozygous mutation in *CAV1*, FPLD7 results from a heterozygous mutation in the gene. *CAV1* gene encodes caveolin-1 [60]. Very few cases of FPLD7 have been reported in humans. These FPLD7 patients share common symptoms and complications of FPLD including deficiency in subcutaneous fat, poor weight gain, development of congenital cataracts, insulin resistance, hyperlipidemia, and muscle weakness [62].
