**Author details**

*Vector-Borne Diseases - Recent Developments in Epidemiology and Control*

**Acknowledgements**

Janeiro—FAPERJ.

**Conflict of interest**

The authors declare no conflict of interest.

NGS next generation sequencing DNA deoxyribonucleic acid RNA ribonucleic acid

VIP virus identification pipeline

RdRp RNA-dependent RNA polymerase

SIFT sorting intolerant from tolerant

RT-qPCR real time quantitative polymerase chain reaction

**Appendices and nomenclature**

*TAR-VIR* targeted viral

ZIKV Zika virus WNV West Nile virus

YFV yellow fever virus DENV dengue virus CHIKV Chikungunya virus

bioinformatics particularly leverage large genomic datasets to determine pathogenic organisms responsible for the outbreak, the origin of the infection and mutations responsible unique phenotypic traits. This information is crucial for effective planning interventions and combating outbreaks. An area of research interest that remains to be explored is the development of online platforms to perform functional analyses of statistically significant mutations in arboviruses. This information is invaluable in the development of vaccines and identification of drug targets.

This work was supported by the ZiBRA2 project supported by the Brazilian Ministry of Health (SVS-MS) and the Pan American Organization (OPAS) and founded by Decit/SCTIE/MoH and CNPq (440685/2016-8 and 440856/2016-7); by CAPES (88887.130716/2016-2100, 88881.130825/2016-2100 and 88887.130823/2016- 2100). MG is supported by Fundação de Amparo à Pesquisa do Estado do Rio de

**28**

Vagner Fonseca1,2, Joilson Xavier2 , San Emmanuel James1 , Tulio de Oliveira1 , Ana Maria Bispo de Filippis3 , Luiz Carlos Junior Alcantara2,3 and Marta Giovanetti2,3\*

1 KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), College of Health Sciences, University of KwaZuluNatal, Durban, South Africa

2 Laboratório de Genética Celular e Molecular, ICB, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

3 Laboratório de Flavivírus, Instituto Oswaldo Cruz Fiocruz, Rio de Janeiro, Brazil

\*Address all correspondence to: giovanetti.marta@gmail.com

© 2019 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
