*8.1.2 Low-dose acetylsalicylic acid*

Low dose acetylsalicylic acid, as known as, "low dose aspirin" (LDA) is recommended in all women with SLE during pregnancy, it should be started during pre-conception period in case of a planned pregnancy and no later than 16 weeks. LDA (75-150 mg/day) has proved to reduce the risk of pre-eclampsia and its complications, regardless the presence of aPLs [56].
