Preface

Systemic lupus erythematosus (SLE) is a multisystem, immune-mediated, inflammatory disease of unknown etiology. Lupus has always featured a broad spectrum of disease-related manifestations that pose significant challenges to successful intervention.

This book presents scientific updates in specific clinical situations to provide meaningful insight into effective control strategies for SLE in rheumatology practice. Chapter authors provide comprehensive information on difficult-to-treat disease-related problems and their evidence-based lines of management. The book begins with a brief guide to diagnosing disease with a vast array of heterogeneous manifestations and mimics. The next section provides an update on lupus kidney disease. Considering the frequency and burden of lupus renal disease, the authors provide a full section on updates in the diagnosis and therapy of lupus nephritis. The next section focuses on endocrinopathies in lupus followed by a section on lupus and pregnancy. The final section examines advances in disease-targeted therapy as well as current and future perspectives.

To my husband Hesham, daughter Maya, and son Karim, who have always inspired and encouraged me not to give up on my dreams.

## **Reem Hamdy A. Mohammed**

Professor of Rheumatology and Clinical Immunology, Department of Rheumatology and Rehabilitation, School of Medicine, Cairo University, Cairo, Egypt

**1**

Section 1

Systemic Lupus

Erythematosus: Pick the Case

Section 1
