*8.2.4 Intravenous immunoglobulin*

Intravenous immunoglobulin (IVIG) is an immunomodulator that regulates the inflammatory processes through anti-idiotype mechanisms. Although it crosses the placenta after the 2nd trimester and in a more significant way after the 3rd trimester, no fetal malformations have been reported. Hence, it is considered a drug compatible with pregnancy [62].
