Systemic Lupus Erythematosus: Pick the Case

**3**

**Chapter 1**

**Abstract**

**1. Introduction**

*Stephen Soloway*

Don't Miss Lupus

lupus as simply one of various other scenarios.

**1.1 Hallmarks of systemic lupus erythematosus**

**1.2 Most recent development for lupus treatment**

it to no longer bind to and stimulate the autoreactive B cell.

**Keywords:** lupus, Sjogren's, Raynaud's, ANA, DNA, DRV VT

system is excluded, when diagnosing and treating a lupus patient.

Chapter for Lupus Book Systemic lupus erythematosus is a well-recognized multi-system disease. Hallmarks of the disorder include the prevalence of antinuclear antibodies (ANA) and double stranded antibodies (DNA). The disease often presents with lupus rashes and/or arthritis or arthralgias. Lupus is "the great imitator," as no organ system is excluded, when diagnosing and treating a lupus patient. While lupus remains evasive in novel therapies with true benefit; one issue has been consistent, in that the preponderance of the evidence thus far, leads to B cell dysfunction. More recently Belimumab was indicated for use in lupus patients. This is a BLyS-Specific inhibitor (B lymphocyte stimulator) medication. At this time, I would like to focus on lupus in a manner that you are not used to hearing. Typically, any practitioner who approaches a patient with a plethora of symptoms, would order blood tests, and conclude a diagnosis of lupus. In this chapter, I will point out and focus on the need to think "outside the box" and perhaps consider

Systemic lupus erythematosus is a well-recognized multi-system disease [1]. Hallmarks of the disorder include the prevalence of antinuclear antibodies (ANA) and double stranded antibodies (DNA). The disease often presents with rashes and/or arthritis or arthralgias. Lupus is "the great imitator," as no organ

While lupus remains evasive in novel therapies with true benefit; one issue has been consistent, in that the preponderance of the evidence thus far, leads to B cell dysfunction. More recently Belimumab was indicated for use in lupus patients, which is an immunomodulator B-Lymphocyte Stimulator (BLyS)-Specific Inhibitor. This drug was approved by the Food and Drug Administration (FDA) for use in lupus patients in 2011 [2]. The majority of patients afflicted with lupus, autoreactive B-cells remain in the body longer than necessary. Belimumab binds to BLyS, causing

Information recently discussed at the ACR2020, provides evidence of Belimumab standard therapy ameliorating the outcome for patients with active renal lupus. A combination of Belimumab, with either mycophenolate mofetil or
