**2.10 Haematopoietic system**

The increase in erythropoiesis results from both a direct effect of thyroid hormones on the erythroid marrow and increased production of erythropoietin. Association of pernicious anaemia can be there in 3% of Graves of which 3% have auto-antibodies to intrinsic factor; accelerated clearance of the vitamin K-dependent clotting factors. Therefore, the dosage of warfarin needs to be reduced in thyotoxicosis [15].

**Figure 2.** *Patient of Graves disease showing diffuse goitre and eye signs.*
