**5. Summary and conclusion**

As the world's population ages, MCC is becoming increasingly common around the world. Thus, every clinician, whether a general practitioner or a specialist, should become increasingly aware of the clinical relevance and undeniable burden (with higher risk of the inappropriate medication, excessive healthcare utilization, and paying high cost) of multiple physical, cognitive and/or mental chronic condition clusters. However, the transition from a single disease-focused perspective to a patient-centered holistic approach may require spending considerable time and tremendous effort for the health professionals and healthcare providers. It is obvious that there is a growing need for population based research in MCC. Considering current approaches and strategies for screening, care and treatment of MCC, more studies and guidelines are still needed to improve our understanding of MCC, to best address the specific chronic health conditions that constitute MCC, to anticipate and screening groups of people at risk of MCC, as well as to increase potential areas for successful intervention and innovation.
