*4.1.6 Melt granulation*

In this process, powder agglomeration is attained by the addition of binding agent which melts at relatively low temperature such as Gelucire®, lecithin, partial glycerides or polysorbates [92]. While the liquid SEDDS is adsorbed to neutral carriers such as silica and magnesium aluminometasilicate [93]. Melt granulation is advantageous compared to wet granulation since it is a 'one-step' process in which the addition of granulating liquid and the following drying phase are absent [74].
