**6. Conclusions**

Foot-and-mouth disease will reduce the milk production of sick animals; severe cases will cause acute death; animal husbandry production caused a great loss, so many countries in the world to foot-and-mouth disease as the most important animal quarantine object. In the world, the United States and other developed countries have completely eliminated foot-and-mouth disease; however, in the developing countries, foot-and-mouth disease still exists. There are seven serotypes of FMD virus, which cannot be immune to each other due to their different antigens. Vaccination is a reliable and effective method for specific prevention of FMD, and a safe and effective vaccine is a prerequisite for the successful prevention, control, and eventual elimination of FMD. Therefore, in order to effectively prevent and control foot-and-mouth disease, it is necessary to thoroughly study the mechanism of action of the virus and develop more effective prevention and control methods to ensure the healthy development of animal husbandry.
