*6.2.7 Immunomodulatory effect*

Clinical trials direct that fructose and FOS supplementation can reduce the influx of clinical inflammation, abridged level in cytokine interleukin (IL)-1α, and necrosis factor-α in ulcerative colitis by *Bacillus longum*. A shoot-up in IL10 positive mucosal dendritic due to inulin, fructose, and FOS intake was displayed in patients with Crohn's illness [52].
