**4.6 Retinoic acid**

Topical tretinoin, although currently recommended for the treatment of acne, has also been reported to be of benefit in plane warts. A study of 25 children with plane warts treated with 0.05% topical tretinoin cream (applied once daily for 6 weeks) was compared with a control group of 25 untreated children. After 12 weeks, clearance of warts was observed in 84.6% of the treated group as compared with 32% of the control group. It was well tolerated with some redness and peeling in 42.3% of the treated group [19].
