**Abstract**

In a survey of adolescents aged 14–17 years, we found that 25% already have experience of sexual contact and they do not know the methods of contraception and neglect condoms. About 77.6% of sexually active adolescent girls had genital infection, including HPV 52.7%, highly oncogenic types 37.9%, and mixed infections 51.4%. Adolescents are extremely vulnerable to HPV-related diseases. Cervical cancer takes the 2nd place in the structure of cancer in women in KHMAO-Ugra and the 1st place at the age of 30 years. Since 2009, girls have been vaccinated against HPV in Ugra. Over 10 years, there was a 39% decrease in the incidence of anogenital warts. We meet with parents, provide information about the risks of HPV infection, expose myths, and discuss the safety and effectiveness of HPV vaccines. Our goal is to win the trust of parents in vaccines, resist anti-vaccine propaganda, increase motivation, and reduce the number of refusal.

**Keywords:** papillomavirus, vaccination, cervical cancer, anogenital warts, adolescent reproductive behavior
