**1. The problem of HPV in Russia and in the Khanty-Mansiysk autonomous region-Ugra**

Human papillomavirus (HPV) is the most frequent sexually transmitted infection. The prevalence of HPV in the world is about 10%.

HPV is the cause of a wide range of serious diseases in both men and women, including cancer and precancerous lesions of the cervix, vulva and vagina, anogenital area and anal canal, penis, and oropharynx, and also plays a crucial etiological role in the development of anogenital warts in both sexes [1–4]. Anogenital (venereal) warts are the most common clinical manifestation of HPV infection. More than 90% of all cases of anogenital warts are caused by 6 and 11 types of HPV. These types of HPV are also responsible for the development of recurrent respiratory papillomatosis [1–3, 5].

The problem of HPV infections during pregnancy can lead to complications such as intrauterine and intrapartum infections of the fetus, increased frequency of cesarean sections, and the risk of developing laryngeal papillomatosis of the larynx of the newborn, increasing the risk of infant mortality and the number of surgical interventions on the cervix for severe dysplasia in young women with risk of complications for subsequent pregnancies—spontaneous abortions and premature births.
