**5. Conclusion**

Burn injury is one of the most severe forms of trauma that is related with significant pain and various physical, psychological, and social diminishments; therefore, the exploration of advanced treatment strategies in order to obviously heal and reduce the lifelong burn wound recovery phases is demanding. Burn animal models have been proposed as valuable tools that provide considerable insights into the burn pathophysiology as well as for investigating the properties of new medicines before the clinical use. Accordingly, the standardization of animal models is crucial for all scientific research, and it can merely be achieved with a comprehensive description of the experimental techniques along with their advantages and limitations. With a better understanding of burn underlying phenomenon as animal models paved the road to its mechanisms, progressive research is expected to continuously identify novel treatment strategies to improve the quality of life for burn patients.

## **Acknowledgements**

The authors would like to thank Prof. Jiang-Chuan Liu and Prof. Nien-Hsien Liou (Department and Graduate Institute of Biology and Anatomy, National Defense Medical Center, Taipei, Taiwan (ROC)) for the knowledge and moral support and also Dr. Chih-Hsin Wang (Department of Plastic and Reconstructive Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan (ROC)) for his helpful discussion during this chapter writing.
