**Author details**

João Victor Nani1,2, Benjamín Rodríguez1 , Fabio Cardoso Cruz1 and Mirian Akemi Furuie Hayashi1,2\*

1 Department of Pharmacology, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil

2 National Institute for Translational Medicine (INCT-TM, CNPq/FAPESP/CAPES), Brazil

\*Address all correspondence to: mhayashi@unifesp.br; mirianhayashi@yahoo.com

© 2019 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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*Animal Models in Psychiatric Disorder Studies DOI: http://dx.doi.org/10.5772/intechopen.89034*

[1] Sansone RA, Sansone LA. Psychiatric disorders: A global look at facts and figures. Psychiatry. 2010;**7**(12):16-19

[10] Vervliet B, Raes F. Criteria of validity in experimental

Medicine. 2012;**43**(11):2241-2244

1978;**276**(5688):565-570

2001;**294**(5544):1030-1038

2011;**50**(21):4774-4807

Science. 2016;**6**(1):5

2010;**167**(7):748-751

2010;**36**(6):1061-1062

psychopathology: Application to models of anxiety and depression. Psychological

[11] Lewis E. A gene complex controlling segmentation in drosophila. Nature.

[12] Kandel ER. The molecular biology of memory storage: A dialogue between genes and synapses. Science.

[13] Hulme SE, Whitesides GM. Chemistry and the worm: Caenorhabditis elegans as a platform for integrating chemical and biological research. Angewandte Chemie International Edition in English.

[14] Surís A, Holliday R, North CS. The evolution of the classification of psychiatric disorders. Behavioral

[15] Insel T, Cuthbert B, Garvey M, Heinssen R, Pine DS, Quinn K, et al. Research domain criteria (RDoC): Toward a new classification framework for research on mental disorders. American Journal of Psychiatry.

[16] Cuthbert BN, Insel TR. Toward new approaches to psychotic disorders: The NIMH research domain criteria project. Schizophrenia Bulletin.

[17] Cuthbert BN. The RDoC framework: Facilitating transition from ICD/DSM to dimensional approaches that integrate neuroscience and psychopathology. World Psychiatry. 2014;**3**(1):28-35

[18] Greenwood TA, Shutes-David A, Tsuang DW. Endophenotypes in schizophrenia: Digging deeper to identify genetic mechanisms. Journal

[3] Alexandrov V, Brunner D, Hanania T, Leahy E. High-throughput analysis of behavior for drug discovery. European Journal of Pharmacology.

[4] Salgado JV, Sandner G. A critical overview of animal models of psychiatric disorders: Challenges and perspectives. Revista Brasileira de Psiquiatria. 2013;**35**(2):77-81

[5] Lema YY, Gamo NJ, Yang K, Ishizuka K. Trait and state biomarkers for psychiatric disorders: Importance of infrastructure to bridge the gap between basic and clinical research and industry. Psychiatry and Clinical Neurosciences.

[6] Kesby JP, Eyles DW, McGrath JJ, Scott JG. Dopamine, psychosis and schizophrenia: The widening gap between basic and clinical

neuroscience. Translational Psychiatry.

[7] McKinney WT, Bunney WE. Animal model of depression. I. Review of evidence: Implications for research. Archives of General Psychiatry.

Psychopharmacology. 1984;**83**(1):1-16

[9] Belzung C, Lemoine M. Criteria of validity for animal models of psychiatric disorders: Focus on anxiety disorders and depression. Biology of Mood & Anxiety Disorders. 2011;**1**(1):9

[2] Swinney DC, Anthony J. How were new medicines discovered? Nature Reviews Drug Discovery.

**References**

2011;**10**(7):507-519

2015;**750**(5):82-89

2018;**72**(7):482-489

1969;**21**(2):240-248

[8] Willner P. The validity of animal models of depression.

2018;**8**:30

*Animal Models in Psychiatric Disorder Studies DOI: http://dx.doi.org/10.5772/intechopen.89034*
