**4. Conclusions**

*Drosophila* Grs, IRs, Trp, and ppk receptors underlie detection of various categories of tastants but a lot remains undetermined about the composition and response properties of taste receptors. How combinations of GRs and IRs belonging to different receptor families (e.g. Gr and IR), coordinate within the neurons that house them is a subject of investigation. Feeding behavior is root cause of metabolic disorders. A better understanding of the biology of metabolic disorders in association with GRs, IRs, Trp, and ppk receptors is a need of the hour because of the burden of metabolic disorders, high incidences of cardiovascular diseases, faster

aging, dependence on readymade food and consumption of unhealthy junk food in kids. A better understanding of the IRs and other receptors, neural circuits, higher order neurons involved in taste modulation as well as food regulation could provide us with a better understanding about human metabolic disorders and lead to a subsequent development of treatment strategies ultimately benefitting mankind. Recent reports invite exciting new avenues of investigation to determine the higher brain locations that receive taste input from the AMMC, and to trace the circuits by which information is relayed to motor neurons and neurons of the mushroom body to control feeding behavior and associations with appetitive and aversive learning.
