**Abstract**

Patients with unilateral hearing loss have impaired hearing of sounds coming from the affected side, decreased comprehension of speech in noisy environments, and lack of sound localization. There are many conditions that can induce unilateral hearing loss, but idiopathic sudden sensorineural hearing loss (ISSHL) is thought to be most notable because of its high incidence. Patients with ISSHL suddenly acquire unilateral hearing loss; therefore, there are additional significant health problems that complicate the abovementioned symptoms due to the characteristic clinical course of ISSHL including hearing-related discomfort, tinnitus, and anxiety. It has been reported that hearing-related discomfort is closely associated with patients' quality of life. In this chapter, the associated health issues of patients with ISSHL are described, and the interventions employed for patients with unilateral hearing loss are evaluated for their potential in improving the lives of ISSHL patients.

**Keywords:** idiopathic sudden sensorineural hearing loss, bone-anchored hearing aids, contralateral routing of signals, cochlear implant, hearing-related discomfort
