Contents

#### **Preface XI**


Chapter 6 **The Mechanisms of Proliferation and Energy Metabolism in Oral Cancer 83** Masakatsu Fukuda and Hideaki Sakashita

Preface

Oral cancer is frequently diagnosed late, when the disease has advanced with lesions that are large and deeply invasive and with metastasis to regional lymph nodes, leading to in‐ creased mortality. Moreover, late diagnosis and treatment often result in considerable mor‐ bidity of oral and maxillofacial structures and poor appearance and function following therapy. Incidence of cancer in the country has been increasing over the last few decades. This book covers the topic of oral cancer in a concise but detailed manner. The book certain‐ ly achieves its aim: enhancing knowledge of the many aspects of care and management that oral cancer encompasses. The opening chapter presents the pathogenesis of cancer by intro‐ ducing the reader to the cellular, histological, and molecular changes that occur in the dis‐ ease process. This is followed by detailed chapters on different, newer aspects of oral cancer, which will enrich all clinicians who aim to promote preventive advice. Overall, the book

This book will help researchers and clinicians in understanding the fundamentals and man‐

**Dr. S. Sundaresan M.Sc., M.Phil., Ph.D.**

SRM Institute of Science and Technology

Department of Medical Reserch

Associate Professor

India

fulfills its purpose entirely in updating researchers on oral cancer.

agement of oral cancer in individual patients.
