**4. Mitochondrial DNA repair machinery**

Most of the repair pathways used by mitochondria to deal with its damaged DNA are quite similar to those operating in the nucleus; this observation makes

 sense when we realize that mitochondrion relies completely in import of DNA repair elements encoded by nuclear genome, despite that mitochondrial genome does not contain any gene implicated in repair; it appears that the mitochondrial version of the repair machinery operates with fewer proteins than the nuclear counterparts [33] (**Figure 1**).
