**6. Concluding remarks**

 After decades of study, it has been concluded that like nucleus, mitochondria do possess specific mechanisms to maintain integrity of its small and polyploid genome, and although nowadays, the complete repertoire of elements participating in mtDNA repair has not been identified, it appears that these pathways resemble those of nucleus but operating with fewer elements. In addition, mitochondria have evolved organelle specific mechanisms which work as a backup when the repair pathways are surpassed by the amount of damage and that would be impossible to carry out in nuclear genome. In conclusion, the repair of mitochondrial genome is a field in continuous growth that promises new discoveries in the years to come.

*DNA Repair - An Update* 
