**6. Conclusion**

*Indoor Environment and Health*

chi-square test [19].

[post-admission] – [pre-admission] [18].

to pollen [18]. Prior to and following occupation of the rooms, participants completed a questionnaire regarding symptoms and mood (a POMS (profiles of mood status) questionnaire was employed), and a variety of blood tests were performed including peripheral blood counts, liver and kidney functions, minerals, specific Ig E for various allergens, and cytokines. The measured items were represented as

The results of the questionnaire of symptoms and mood are shown in **Figure 4**. In the upper panel, it can be seen that nasal obstruction, lacrimation, and difficulty of daily life improved in participants occupying the CCSNOP rooms compared with those occupying the NWC rooms. However, eye redness became worse in participants occupying the CCSNOP rooms. In the lower panel, moods for "tension and anxiety," "depression," and "fatigue" improved in participants occupying the CCSNOP rooms compared with those occupying the NWC rooms. Additionally, total mood disturbance also improved. All of these statistical analyses employed the

Total Ig E was found to increase slightly but significantly in participants occupying the CCSNOP rooms compared with those occupying the NWC rooms. Moreover, the percentage of eosinophils also increased in participants occupying the CCSNOP rooms. The reason for the changes in IgE and eosinophils remains unclear. Our experiment comprised just a 1-hour stay. Thus, although symptoms and moods may

change rapidly, IgE and eosinophils changes may require more time [19].

*Results of the symptom questionnaire and POMS. Statistical data were analyzed by the chi-square test.*

**80**

**Figure 4.**

We have presented the outcome of two different strategies aimed at improving human health by modification of indoor environments. A consideration of several factors is required to maintain human health and minimize physical and mental disturbances while indoors, including the avoidance of chemical substances such as VOCs and other chemicals. Future investigations will involve participants occupying variously modified rooms (including NCPDIAC and SNCBOP) for longer periods of time. These studies should contribute toward the creation of healthy indoor environments for human habitation.
