**Author details**

*Extracellular Vesicles and Their Importance in Human Health*

The EVs emerge as a powerful tool for early diagnosis and subsequent prevention of pathologies with high risk for the brain dysfunction. Still, EVs investigation as biomarkers and therapeutic agents is in its infancy. There is increasing evidence that EVs have an important role in brain pathophysiology. Thus, their potential application as prognostic and diagnostic biomarkers and targeted therapeutic tools relies on their subsequent isolation for molecular and functional characterization that can relate them with the cellular source and cellular mechanisms in both health

This work was supported by grants of UEFISCDI, projects no. PN-III-P1- 1.2-PCCDI-2017-0527 and PN-III-P1-1.2-PCCDI-2017-0797 and the Romanian Academy and Romanian Ministry of Research and Innovation, projects no.

The authors declare that the research was conducted in the absence of any either commercial or financial relationships that could be construed as a potential conflict

**7. Conclusion**

and disease.

**Acknowledgements**

**Conflict of interest**

of interest.

1N/2019\_19.29.01.02 and 7PFE/16.10.2018.

**146**

Laura Cristina Ceafalan1,2, Octavian Costin Ioghen1,2, Daciana Silvia Marta1 , Alina Constantin3 , Nicoleta Alexandru3 , Miruna Nemecz<sup>3</sup> , Gabriela Tanko3 , Alexandru Filippi3 , Stefania Lucia Magda2,4, Florina Bojin5,6, Virgil Paunescu5,6, Dragos Vinereanu2,4, Adriana Georgescu3 and Mihaela Gherghiceanu1,2\*

1 Victor Babeș National Institute of Pathology, Bucharest, Romania

2 Carol Davila University of Medicine, Bucharest, Romania

3 Pathophysiology and Pharmacology Department, Institute of Cellular Biology and Pathology, 'Nicolae Simionescu' of Romanian Academy, Bucharest, Romania

4 Cardiology Department, University and Emergency Hospital Bucharest, Bucharest, Romania

5 Department of Functional Sciences, 'Victor Babeș' University of Medicine and Pharmacy Timisoara, Timisoara, Romania

6 'Pius Brinzeu' Clinical Emergency County Hospital Timisoara, OncoGen-Center for Gene and Cellular Therapies in the Treatment of Cancer, Timisoara, Romania

\*Address all correspondence to: mihaela.gherghiceanu@ivb.ro

© 2019 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
