**3.** *Aloe vera* **(L.) Burm.f.**

*A. vera* is a succulent, evergreen, perennial herb, which is being cultivated all over the world mainly for the purpose of agricultural and medicinal uses. Anthraquinones (aloe-emodin (**1**), chrysophanol (**2**), and a bitter reddish-yellow exudate containing majorly anthrones (aloin A and B (**3**)), aloe-emodin (**4**) [5], and few aloe resins such as aloeresin (**5**) and aloenin **(6)**) [6] are the major constituents in aloe (**Figure 1**). Aloe-emodin **4** is reported to enhance cognition against scopolamine-induced cognitive impairment in mice [7]. Aloin **3** is shown to decrease intracellular ROS generation and reduced Ca2+ production, which is responsible for depolarization and death of the neuron, suggesting it as a useful and alternative therapy for cerebrovascular diseases [8]. *A. vera* gel demonstrated antioxidant and anti-inflammatory activities when given to the rats with sciatic nerve reperfusion injury [9].

**Figure 1.** *Structures of compounds present in* A. vera*.*

*Bioactive Molecules from Indian Medicinal Plants as Possible Candidates for the Management… DOI: http://dx.doi.org/10.5772/intechopen.92043*
